TY - CHAP M1 - Book, Section TI - Acne Vulgaris A1 - Goh, Carolyn A1 - Cheng, Carol A1 - Agak, George A1 - Zaenglein, Andrea L. A1 - Graber, Emmy M. A1 - Thiboutot, Diane M. A1 - Kim, Jenny A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. PY - 2019 T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCEAcne vulgaris is a common disorder of the pilosebaceous unit.There are four key elements of pathogenesis: (1) follicular epidermal hyperproliferation, (2) sebum production, (3) the presence and activity of Propionibacterium acnes, and (4) inflammation and immune response.Clinical features include comedones, papules, pustules, and nodules on the face, chest, and back.Treatment often includes combinations of oral and topical agents such as antimicrobials, retinoids, and hormonal agents. Laser and light sources are additional treatment options. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - dermatology.mhmedical.com/content.aspx?aid=1161325229 ER -