RT Book, Section
A1 Mordorski, Breanne
A1 Friedman, Adam J.
A2 Kang, Sewon
A2 Amagai, Masayuki
A2 Bruckner, Anna L.
A2 Enk, Alexander H.
A2 Margolis, David J.
A2 McMichael, Amy J.
A2 Orringer, Jeffrey S.
SR Print(0)
ID 1161351963
T1 Gram-Negative Coccal and Bacillary Infections
T2 Fitzpatrick's Dermatology, 9e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071837798
LK dermatology.mhmedical.com/content.aspx?aid=1161351963
RD 2024/04/19
AB The  Gram  stain,  developed  in  the  late  1800s  by  Hans  Christian  Gram,  is  used  to  distinguish  2  major  categories  of  bacteria.  Gram-positive  bacteria  retain  the  purple  hue  of  the  initial  crystal  violet  stain,  whereas  Gram-negative  bacteria  are  decolorized  and  subsequently  stain  red  by  safranin  or  carbol  fuchsin.  While  Gram-positive  bacteria  have  thick  walls  of  peptidoglycan  and  secondary  polymers  that  are  relatively  impermeable  and  resist  decolorization,  Gram-negative  bacteria  have  a  thin  peptidoglycan  layer  with  an  outer  lipid  membrane  bilayer  that  is  readily  disrupted  by  this  process.1