RT Book, Section A1 Mentzel, Thomas A1 Brenn, Thomas A2 Kang, Sewon A2 Amagai, Masayuki A2 Bruckner, Anna L. A2 Enk, Alexander H. A2 Margolis, David J. A2 McMichael, Amy J. A2 Orringer, Jeffrey S. SR Print(0) ID 1161337867 T1 Lipogenic Neoplasms T2 Fitzpatrick's Dermatology, 9e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071837798 LK dermatology.mhmedical.com/content.aspx?aid=1161337867 RD 2024/04/19 AB AT-A-GLANCELipogenic neoplasms represent the most frequent mesenchymal neoplasms.Lipogenic neoplasms include benign neoplasms (eg, lipoma, angiolipoma), intermediate, locally aggressive, nonmetastasizing neoplasms (eg, atypical lipomatous tumor), and clearly malignant lesions (eg, pleomorphic liposarcoma).Anatomic site, depth, and size are responsible for striking differences in regard to incidence, morphology, and prognosis.The clinical presentation of lipogenic neoplasms is usually nonspecific.The majority of lipogenic neoplasms is characterized by distinct cytogenetic abnormalities that may have diagnostic and therapeutic value.Surgical excision is the treatment of choice; in cases of malignant neoplasms not amenable for complete excision radiation therapy, however, chemotherapy or target-like therapy may be used.