RT Book, Section A1 Haddock, Ellen S. A1 Friedlander, Sheila Fallon A2 Kang, Sewon A2 Amagai, Masayuki A2 Bruckner, Anna L. A2 Enk, Alexander H. A2 Margolis, David J. A2 McMichael, Amy J. A2 Orringer, Jeffrey S. SR Print(0) ID 1161340632 T1 Poxvirus Infections T2 Fitzpatrick's Dermatology, 9e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071837798 LK dermatology.mhmedical.com/content.aspx?aid=1161340632 RD 2024/04/23 AB AT-A-GLANCEPoxviruses are the largest animal viruses; they can cause disease of varying severity in humans.Smallpox is the only poxvirus whose sole reservoir is humans, which allowed its eradication.The virus used in smallpox vaccines, vaccinia, has its own adverse effects.Monkeypox is a zoonotic infection endemic in Africa.Milker’s nodule and orf mainly cause localized cutaneous infections.Molluscum contagiosum is generally a benign cutaneous disease most frequently seen in children and immunocompromised individuals.Histopathologic features of poxviral cutaneous lesions include the presence of intracytoplasmic eosinophilic inclusion bodies.