RT Book, Section
A1 Liaqat, Maryam
A1 Halpern, Analisa V.
A1 Green, Justin J.
A1 Heymann, Warren R.
A2 Kang, Sewon
A2 Amagai, Masayuki
A2 Bruckner, Anna L.
A2 Enk, Alexander H.
A2 Margolis, David J.
A2 McMichael, Amy J.
A2 Orringer, Jeffrey S.
SR Print(0)
ID 1161342659
T1 The Rickettsioses, Ehrlichioses, and Anaplasmoses
T2 Fitzpatrick's Dermatology, 9e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071837798
LK dermatology.mhmedical.com/content.aspx?aid=1161342659
RD 2024/04/19
AB AT-A-GLANCERickettsiae  primarily  target  vascular  endothelial  cells,  causing  febrile  illness  and  rash  in  the  mammalian  host.Transmission  is  predominantly  via  tick  bites,  with  certain  pathogens  transmitted  by  human  body  lice  and  mites.Fever,  headache,  myalgia,  and  malaise  are  common  to  rickettsial,  ehrlichial,  and  Anaplasma  infections;  rash  is  common  in  rickettsial  disease,  occasional  in  ehrlichial  infection,  and  rare  in  anaplasmosis.The  early  signs  and  symptoms  of  infection  are  often  nonspecific  and  can  mimic  self-limited  viral  illnesses  or  other  life-threatening  illnesses.Early  empiric  treatment  with  doxycycline  should  be  considered  in  highly  suspicious  cases  until  rickettsial  infection  is  definitively  ruled  out,  as  delayed  treatment  can  lead  to  severe  sequelae  and  high  mortality  rates.