RT Book, Section
A1 Krishna, Sheila M.
A1 Garrett, Algin B.
A2 Kelly, A. Paul
A2 Taylor, Susan C.
A2 Lim, Henry W.
A2 Serrano, Ana Maria Anido
SR Print(0)
ID 1161546995
T1 Squamous Cell Carcinoma
T2 Taylor and Kelly's Dermatology for Skin of Color, 2e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071805520
LK dermatology.mhmedical.com/content.aspx?aid=1161546995
RD 2024/04/19
AB KEY  POINTSPrimary  carcinoma  of  the  skin  is  the  most  common  form  of  cancer  diagnosed  in  the  United  States,  but  the  incidence  in  people  with  skin  of  color  is  reported  as  rare.Most  squamous  cell  carcinomas  (SCCs)  in  people  with  skin  of  color  occur  in  non–sun-exposed  areas;  however,  when  SCC  does  occur  in  a  sun-exposed  area,  the  anatomic  distribution  is  similar  to  that  in  Caucasians.SCC  that  occurs  in  sun-exposed  skin  has  its  origin  in  loss  of  the  organized  control  of  epidermal  keratinocyte  differentiation  secondary  to  DNA  damage  as  a  direct  result  of  ultraviolet  light.The  factors  that  are  responsible  for  developing  skin  cancers  in  non–sun-exposed  areas  are  unknown.Areas  of  chronic  inflammation,  chronic  ulceration,  and  scarring  are  predisposed  to  the  development  of  SCC.