RT Book, Section A1 McKinley-Grant, Lynn A1 Peebles, Jon Klinton A2 Kelly, A. Paul A2 Taylor, Susan C. A2 Lim, Henry W. A2 Serrano, Ana Maria Anido SR Print(0) ID 1161549143 T1 Renal Disease T2 Taylor and Kelly's Dermatology for Skin of Color, 2e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071805520 LK dermatology.mhmedical.com/content.aspx?aid=1161549143 RD 2024/04/24 AB KEY POINTSAll adults and children with renal disease can develop skin complications—these may arise from the uremic state or be due to the medical treatment received for the condition, for instance dialysis or kidney transplantation.More than 20 million people aged 20 years or older in the United States alone have chronic kidney disease, which is fatal if not treated with dialysis or kidney transplantation.The most important causes of chronic renal disease are diabetes and hypertension. Racial factors may play a role in the susceptibility to chronic renal failure because there is a strong association of hypertensive end-stage renal disease in African American families.Cutaneous manifestations are to be expected in any patient who undergoes dialysis treatment. Many of the skin changes that occur in patients with chronic renal failure are also found in patients undergoing dialysis.In contrast to dialysis treatment, cutaneous signs of renal failure may actually resolve if renal transplantation is successful.However, posttransplant patients are at risk of developing primary cutaneous malignancies as well as cutaneous and mucosal lesions. It is particularly important to recognize the latter in pediatric patients with skin of color, as they are more common in African American and Hispanic children.