RT Book, Section
A1 Horn, Thomas D.
A1 Junkins-Hopkins, Jacqueline M.
A2 Barnhill, Raymond L.
A2 Crowson, A. Neil
A2 Magro, Cynthia M.
A2 Piepkorn, Michael W.
A2 Kutzner, Heinz
A2 Desman, Garrett T.
SR Print(0)
ID 1178387622
T1 Interface Dermatitis
T2 Barnhill's Dermatopathology, 4e
YR 2020
FD 2020
PB McGraw Hill Education
PP New York, NY
SN 9780071828222
LK dermatology.mhmedical.com/content.aspx?aid=1178387622
RD 2024/04/20
AB A  large  group  of  skin  diseases  is  characterized  by  histologic  changes  categorized  as  interface  dermatitis  (Fig.  3-1).  At  a  minimum,  a  variable  combination  of  leukocyte  infiltration  of  the  dermis,  vacuolar  change  of  the  basilar  epidermis,  accumulation  of  melanophages  in  the  upper  dermis,  and  necrosis  of  keratinocytes  must  be  observed.  The  term  “interface  dermatitis”  is  therefore  apt  because  these  findings  occur  at  the  interface  between  the  epidermis  and  dermis.  This  common  thread  binds  otherwise  disparate  entities  together.  Other  terms  applied  to  this  group  of  disorders  include  vacuolar  dermatitis,  vacuolar  interface  dermatitis,  and  lichenoid  tissue  reaction.  Before  considering  specific  diseases,  a  definition  and  illustration  of  the  common  histologic  findings  are  in  order.