Skip to Main Content



  • Erythema multiforme shares the same morphologic appearance across skin types, including a targetoid plaque with a central patch or bullae, but overall varies in color in different skin types.

  • In darker skin, it can be pink-brown to violaceous to dark brown. In the latter cases, it can be harder to see the peripheral halo rim.

  • In lighter skin, it tends to be pink to red centrally with a more visible peripheral halo rim that is hypopigmented to light pink.


FIGURE 41-1.

Pink to violaceous plaques with pink vesicular centers on the dorsal hand. (Reproduced with permission from Wolff K, Johnson RA, Saavedra AP, et al. Fitzpatrick’s Color Atlas and Synopsis of Clinical Dermatology, 8th ed. New York, NY: McGraw Hill; 2017, Figure 27-38.)

FIGURE 41-2.

Targetoid plaques with brighter pink centers exhibiting early vesicular changes and a pale pink rim on the dorsal hand. (Reproduced with permission from Barnhill RL, Crowson AN, Magro CM, et al. Barnhill’s Dermatopathology, 4th ed. New York, NY: McGraw Hill; 2020, Figure 3-7A.)

Pop-up div Successfully Displayed

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.