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Therapeutic Approach

Epidermodysplasia verruciformis (EV) is a rare genetic disease that leads to an abnormal susceptibility to cutaneous infections with a large number of genus β human papilloma viruses. Patients with EV present with generalized verrucae planae, pityriasis versicolor-like macules, and an early development of squamous cell carcinomas (SCC), especially in sun-exposed areas. There is currently no cure for EV. Patients require lifelong monitoring for skin cancer and education regarding strict sun protection. Treatment is aimed at alleviating the skin lesions. See Table 100-1.

Table 100-1Epidermodysplasia Verruciformis Treatment Table

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