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Therapeutic Approach

Necrotizing fasciitis (NF) is a life-threatening skin and soft tissue infection along fascial planes that can affect both healthy and immunocompromised patients. NF can be classified as monomicrobial or polymicrobial. Treatment requires immediate surgical intervention, empirical antibiotic treatment, and intensive care for hemodynamic and metabolic support. Prompt blood and tissue cultures are essential in identifying the culprit organism(s). See Table 136-1.

Table 136-1Necrotizing Fasciitis Treatment Table

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