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Therapeutic Approach

Anetoderma is a rare disorder characterized histologically by a loss of elastic tissue in the dermis. Clinically, lesions consist of multiple, circumscribed areas of flaccid skin that may be associated with wrinkling, atrophic depressions, or saccular protrusions. While primary anetoderma occurs in areas of previously normal skin, secondary anetoderma develops at sites of previous dermatoses. Both primary and secondary types of anetoderma may be associated with underlying systemic conditions, including antiphospholipid syndrome, thus warranting further evaluation. Anetoderma is a benign condition with no regularly effective treatment at the present time. There are no reports of spontaneous regression. In secondary anetoderma, treatment of the primary skin disorder resulting in anetoderma may reduce the risk of developing new lesions. See Table 57-1.

Table 57-1Anetoderma Treatment Table

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