The developing fetus can potentially be affected by any medication given to the mother. The disastrous effects of thalidomide and stilbestrol on the exposed offspring led to the development of the U.S. Food and Drug Administration (FDA) categories that are now assigned before a drug is released.
Table C-1 lists safe treatments for dermatologic diseases in pregnancy, and the common dermatologic diseases and drugs used for them. Previously, drugs were categorized by the letters A, B, C, D and X to classify safety during pregnancy. A new labeling system was implemented in 2015 to help make more informed decisions.
TABLE C-1Safe Treatments for Dermatologic Disorders During Pregnancy ||Download (.pdf) TABLE C-1 Safe Treatments for Dermatologic Disorders During Pregnancy
|Topical clindamycin, erythromycin, benzoyl peroxide
|Topical metronidazole, azelaic acid
|Topical glucocorticoids, calcipotriol, broadband UVB
|Topical glucocorticoids, chlorpheniramine or diphenhydramine
|Genital human papillomavirus infection
|Liquid nitrogen, trichloroacetic acid
|Herpes simplex virus infection
|Penicillins, cephalosporins after first trimester, azithromycin
TABLE C-2Current FDA Categorization for Drugs Used During Pregnancy and Breastfeeding ||Download (.pdf) TABLE C-2 Current FDA Categorization for Drugs Used During Pregnancy and Breastfeeding
|Pregnancy (includes labor and delivery):
|Females and Males of Reproductive Potential