TY  - CHAP
M1  - Book, Section
TI  - Lentigo Maligna
A1  - Karnes, Jonathan B.
A1  - Mayeaux, Jr., E.J.
A1  - Usatine, Richard P.
A2  - Usatine, Richard P.
A2  - Smith, Mindy A.
A2  - Mayeaux, Jr., E.J.
A2  - Chumley, Heidi S.
PY  - 2019
T2  - The Color Atlas and Synopsis of Family Medicine, 3e
AB  - A  67-year-old  man  noted  that  a  brown  spot  on  his  face  was  growing  larger  and  darker  (Figure  175-1).  Dermoscopy  was  performed,  and  polygonal  lines  and  rhomboidal  structures  were  seen  around  the  follicular  openings  (Figure  175-2).  A  broad  shave  biopsy  of  the  whole  lesion  showed  lentigo  maligna  (LM)  (melanoma  in  situ).  The  patient  had  a  long  history  of  multiple  skin  cancers  including  multiple  thin  melanomas  on  his  back.  He  also  had  cardiac  problems  and  was  on  Coumadin.  The  options  for  treatment  were  presented,  and  he  chose  to  try  topical  imiquimod.  He  was  instructed  to  apply  the  imiquimod  daily  to  the  involved  area  and  was  seen  monthly.  After  2  months  it  was  obvious  that  he  was  having  an  exuberant  inflammatory  response  to  the  imiquimod  as  desired  (Figure  175-3).  He  completed  the  3-month  course.  Three  months  after  completion  his  face  appeared  completely  clear  (Figure  175-4)  clinically  and  dermoscopically.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - dermatology.mhmedical.com/content.aspx?aid=1164361374
ER  -