TY - CHAP M1 - Book, Section TI - Psoriasis A1 - Gudjonsson, Johann E. A1 - Elder, James T. A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. PY - 2019 T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCEWorldwide occurrence; affects 2% to 3% of Americans; prevalence ranges from 0.1% to 3% in various populations.A chronic disorder with polygenic predisposition combined with triggering environmental factors such as trauma, infection, or medication.Erythematous scaly papules and plaques; pustular and erythrodermic eruptions occur.Most common sites of involvement are the scalp, elbows, knees, hands, feet, trunk, and nails.Psoriatic arthritis occurs in 10% to 25% of patients; pustular and erythrodermic forms may be associated with fever.Pathology of fully developed lesions is characterized by uniform elongation of the rete ridges, with dilated blood vessels, thinning of the suprapapillary plate, and intermittent parakeratosis. Epidermal and perivascular dermal infiltrates of lymphocytes, with neutrophils occasionally in aggregates in the epidermis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - dermatology.mhmedical.com/content.aspx?aid=1161323116 ER -