TY - CHAP M1 - Book, Section TI - Hydroa Vacciniforme A1 - Vandergriff, Travis A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. PY - 2019 T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCEA rare, chronic, scarring photodermatosis sometimes associated with Epstein-Barr virus infection.Characterized by recurrent sunlight-induced crops of papulovesicles and vesicles, most commonly on the face and dorsa of the hands.Onset commonly in childhood, remitting most often at puberty.May be a scarring variant of polymorphic light eruption.Focal intraepidermal vesiculation, reticular degeneration of the epidermis, epidermal and upper dermal necrosis, and sometimes ulceration are typical histologic changes.Avoidance of ultraviolet radiation including the use of broad-spectrum sunscreens is the only established therapy, but there may be a role for antivirals.A severe, often fatal lymphoma resembling hydroa vacciniforme is distinguished by fever, facial edema, and systemic symptoms. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - dermatology.mhmedical.com/content.aspx?aid=1161327183 ER -