TY - CHAP M1 - Book, Section TI - Tuberculosis and Infections with Atypical Mycobacteria A1 - Sethi, Aisha A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. PY - 2019 T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCEInfection with Mycobacterium tuberculosis or other very closely related strains, as well as the inflammatory reaction of the host define, the disease (tuberculosis [TB]).One-third of the world’s population is infected with TB.TB is the main cause of death of patients infected with HIV.TB usually affects the lung, but virtually all other organ systems may be involved.TB of the skin is a relatively rare manifestation with a wide spectrum of clinical findings depending on the source of infection and the immune status of the host.Diagnosis is based on clinical manifestations, histopathologic analysis, demonstration of the relevant mycobacteria in tissue or in culture and host reaction to M. tuberculosis antigen.Treatment is with standard multidrug regimens; cases of multidrug-resistant TB or extensively multidrug-resistant TB require special attention.Course and prognosis depend on the immune status of the host. Treatment is curative except for patients with a severely compromised immune system. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - dermatology.mhmedical.com/content.aspx?aid=1161352752 ER -