TY - CHAP M1 - Book, Section TI - Cutaneous Manifestations of HIV and Human T-Lymphotropic Virus A1 - Lipworth, Adam D. A1 - Freeman, Esther E. A1 - Saavedra, Arturo P. A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. PY - 2019 T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCEHIV is a retrovirus that causes immune suppression and dysregulation primarily via depletion of CD4+ lymphocytes and CD4+ cells of monocytic lineage.In spite of better screening programs, availability of antiretroviral therapy (ART), and improved side-effect profiles, new infections continue to be documented.The range of dermatologic complications seen in HIV/AIDS relates to the evolving immunologic state of the patient, specific viral characteristics of the serotype causing infection, the period of time from infection to dermatologic complication, and the length of antiretroviral treatment.Acute HIV infection presents as a mononucleosis-like syndrome that can include a morbilliform exanthem 3 to 6 weeks after infection with HIV.In resource-limited areas, untreated infection may lead to progressive dermatologic disease.In reconstituted individuals and long-term viral suppression, sun-induced neoplasia and viral-induced neoplasia are significant burdens. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - dermatology.mhmedical.com/content.aspx?aid=1161340945 ER -