TY - CHAP M1 - Book, Section TI - Surgical Management of Melanoma A1 - Mattei, Peter L. A1 - Jones, Elizabeth K. A1 - Tsao, Hensin A2 - Avram, Marc R. A2 - Avram, Mathew M. A2 - Ratner, Désirée PY - 2015 T2 - Procedural Dermatology AB - In the past several decades, the incidence of melanoma has steadily risen. In the United States, as of 2012, it is estimated that 76,250 new cases of melanoma will develop and 9,180 patients will die of the disease.1 Data from 2006 to 2008 projects that 1 in 36 males and 1 in 55 females will develop invasive melanoma during their lifetime.1 The median age of diagnosis is 59 years. Furthermore, the projected increase in the incidence of melanoma may be underestimated due to unreported outpatient treatments of superficial and in situ melanomas. Melanoma is one of the leading cancers in terms of average years of life lost per death from disease.2 Melanoma has higher incidence rates in lightly pigmented Caucasians than in Hispanics, Asians, and African Americans.2 Estimates indicate that 82% to 85% of patients present with localized disease, 10% to 13% with regional disease, and 2% to 5% with distant metastatic disease.3 Melanoma is responsible for the majority of skin cancer-related deaths but is often cured when detected early. Outcome depends on the stage at presentation. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - dermatology.mhmedical.com/content.aspx?aid=1175094470 ER -