TY - CHAP M1 - Book, Section TI - Postinflammatory Hyperpigmentation A1 - Zhu, Yan I. A2 - Alam, Murad A2 - Bhatia, Ashish C. A2 - Kundu, Roopal V. A2 - Yoo, Simon S. A2 - Chan, Henry Hin-Lee PY - 2009 T2 - Cosmetic Dermatology for Skin of Color AB - Postinflammatory hyperpigmentation (PIH) primarily affects dark-skinned individuals (Fitzpatrick Skin Phototype III through VI) or lighter-skinned individuals with dark irides and has no gender predilection (Figure 17.1). With the increasing ethnic diversity of the United States, dermatologists will encounter more inquiry about PIH. Postinflammatory hyperpigmentation often leads to anxiety in individuals, which is sometimes out of proportion to the severity of the condition. This anxiety is aggravated by the fact that there is no quickly effective treatment other than cosmetic cover-ups. Frequently patients are more concerned about the dyschromia and not aware of the inflammatory condition that is causing PIH (Table 17.1, Figure 17.2). The definition of postinflammatory hyperpigmentation, as its name implies, is very straightforward. Other names used for PIH include postinflammatory melanoderma. There are only a few conditions such as melasma, solar lentigo, and drug-induced hyperpigmentation that may mimic PIH. Melasma tends to be macular and has uniform intensity and well-defined borders, while PIH tends to follow the shape and distribution of the preceding inflammation and has irregular pigmentation intensity and indistinct or feathered borders. Solar lentigo appears on the sun-exposed area of a person, typically the face, dorsal arms, and hands. Drug-induced hyperpigmentation should be suspected in individual who have taken such medications as minocycline, chloroquine, bleomycin, mercury, or amiodarone. The pigmentation tends to be symmetrically distributed and may not correlate with preceding inflammation. In the author's opinion, hyperpigmentation at the site of fixed drug eruption should be categorized as PIH. SN - PB - McGraw Hill Medical CY - New York, NY Y2 - 2024/10/06 UR - dermatology.mhmedical.com/content.aspx?aid=1175119196 ER -