TY  - CHAP
M1  - Book, Section
TI  - The Future of Scar Management
A1  - Vu, Michael M.
A1  - Galiano, Robert D.
A1  - Kim, John Y. S.
A2  - Alam, Murad
A2  - Dover, Jeffrey S.
A2  - Waibel, Jill S.
A2  - Arndt, Kenneth A.
A2  - Kim, John Y. S.
A2  - Thomas, J. Regan
A2  - Gaball, Curtis W.
A2  - Chan, Rodney K.
PY  - 2021
T2  - Treatment of Scars From Burns and Trauma
AB  - The  landscape  of  scar  therapy  research  is  in  an  exciting  state  of  intensive  investigation,  with  dozens  of  promising  therapies  being  tested  to  evaluate  their  expanded  role  in  scar  treatment.  Various  emerging  pharmacologic  treatments  may  be  able  to  mitigate  scars  as  they  evolve  or  after  they  are  mature.  It  may  also  be  possible  to  facilitate  healing  and  reduce  scarring  by  employing  mechanical  ways  to  modulate  tension  on  the  skin  near  a  wound.  Investigators  are  also  studying  how  we  might  correct  scarring  with  stem  cells,  which  express  scarless  healing  signaling  pathways.  One  of  the  critical  research  questions  is  identifying  which  stem  cell  niches  are  most  relevant.  While  much  promising  research  is  underway,  there  remains  a  dearth  of  randomized  controlled  trials  to  test  the  comparative  effectiveness  of  different  treatment  strategies.  Further,  despite  the  abundance  of  potential  treatment  candidates  currently  being  investigated  in  preclinical  testing,  there  is  a  relative  paucity  of  drugs  and  devices  in  phase  II  and  III  clinical  trials.  
SN  - 
PB  - McGraw Hill
CY  - New York, NY
Y2  - 2024/04/19
UR  - dermatology.mhmedical.com/content.aspx?aid=1176883816
ER  -