TY - CHAP M1 - Book, Section TI - Basic Science of the Epidermis A1 - Baumann, Leslie S. A2 - Baumann, Leslie S. A2 - Rieder, Evan A. A2 - Sun, Mary D. PY - 2022 T2 - Baumann’s Cosmetic Dermatology, 3e AB - SUMMARY POINTSWhat’s Important?Keratinocytes have multiple receptors that give them several important functions.Every skincare product placed on the skin affects the keratinocytes in some way.Stem cells in cosmeceutical products have no activity.What’s New?Circadian rhythms increase TEWL at night.Keratinocytes focus on cell protection in the daylight and cell repair at night.Cosmeceuticals can manipulate epidermal skin cells.Visible light injures mitochondria and lysosomes, and ages skin.What’s Coming?New research on CBD in skincare products.New treatments to remove lipofuscin and rejuvenate lysosomes.New modalities to protect mitochondria.More studies on the effects of light on keratinocytes. SN - PB - McGraw Hill LLC CY - New York, NY Y2 - 2024/03/29 UR - dermatology.mhmedical.com/content.aspx?aid=1197531936 ER -