TY - CHAP M1 - Book, Section TI - Spirochetal, Protozoal, Mycobacterial, and Rickettsial Diseases A1 - Prose, Neil S. A1 - Kristal, Leonard Y1 - 2017 N1 - T2 - Weinberg's Color Atlas of Pediatric Dermatology, 5e AB - Figure 4-1Congenital syphilis In utero infection by the spirochete Treponema pallidum can occur after the 16th week of gestation. Intrauterine disease, especially during early pregnancy, may result in spontaneous abortion or in a severely affected infant. Severe disease that is present at birth presents with hepatosplenomegaly, ascites, meningoencephalitis, and severe anemia. Osteochondritis is the most characteristic bone change. The cutaneous findings in severe congenital syphilis include bullae, pustules, macules, and papules.Graphic Jump LocationView Full Size||Download Slide (.ppt) SN - PB - McGraw-Hill Education Medical CY - New York, NY Y2 - 2024/03/29 UR - dermatology.mhmedical.com/content.aspx?aid=1133963266 ER -