TY - CHAP M1 - Book, Section TI - Basic Principles of Immunologic Diseases in Skin (Pathophysiology of Immunologic/Inflammatory Skin Diseases) A1 - Nagao, Keisuke A1 - Udey, Mark C. A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. Y1 - 2019 N1 - T2 - Fitzpatrick's Dermatology, 9e AB - AT A GLANCEImmunologic/inflammatory skin diseases result from inappropriate and frequently exaggerated responses to endogenous skin constituents or external stimuli and are orchestrated by leukocytes and nonleukocytes.Disease pathogenesis is often incompletely understood, but select experimental models and skin diseases have provided insight into the pathogenesis of human immunologic/inflammatory skin diseases.This chapter provides examples where disease pathogenesis is reasonably well understood and describes contemporary approaches that have resulted in improved understanding and, in some instances, improved therapy. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - dermatology.mhmedical.com/content.aspx?aid=1161321352 ER -