TY - CHAP M1 - Book, Section TI - Actinic Prurigo A1 - Vandergriff, Travis A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. Y1 - 2019 N1 - T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCEA rare chronic pruritic and excoriated papular or nodular eruption of sun-exposed and, to a lesser extent, nonexposed skin.Beginning in childhood, it may remit at puberty, exacerbate most often in summer, and fade in winter.Indigenous peoples of North and South America are disproportionately affected.Association with HLA-DR4, specifically the HLA- DRB1*0407 and DRB1*0401 variantsPrevention through avoidance of sunlight is the first-line therapy; thalidomide or other immunosuppressive agents may be required. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - dermatology.mhmedical.com/content.aspx?aid=1161327129 ER -