TY - CHAP M1 - Book, Section TI - Morphea and Lichen Sclerosus A1 - Cyrus, Nika A1 - Jacobe, Heidi T. A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. Y1 - 2019 N1 - T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCEOccurs in children and adults.Linear subtype predominates in children.Circumscribed and generalized predominate in adults.A self-limited or chronically relapsing autoimmune disorder targeting the skin with the following major features:Inflammatory, sclerotic, atrophic phases.Thickened sclerotic skin.Systemic disease, including arthritis and neurologic disorders, in a minority.Differentiated from scleroderma by lack of acrosclerosis/sclerodactyly.Complications may cause significant irreversible cosmetic and functional impairment including the following:Atrophy of dermis, fat, and subcutaneous structures.Contracture.Limb-length discrepancy.Bony abnormalities.Effective treatment reduces signs of disease activity and does not produce complete resolution of lesions. Treatment based on the following:Disease subtype.Depth of involvement.Stage (inflammatory, sclerotic, atrophic).Potential for complications. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - dermatology.mhmedical.com/content.aspx?aid=1161332682 ER -