TY - CHAP M1 - Book, Section TI - Cryoglobulinemia and Cryofibrinogenemia A1 - Sartori-Valinotti, Julio C. A1 - Davis, Mark D. P. A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. Y1 - 2019 N1 - T2 - Fitzpatrick's Dermatology, 9e AB - Cryoglobulins are circulating immunoglobulins found in both serum and plasma that reversibly precipitate or gel upon cold exposure. Cryofibrinogens result from precipitation of fibrinogens on cold exposure and are detectable only in plasma samples, not serum. This chapter focuses on conditions that lead to either microvascular occlusion (Type I cryoglobulinemia and cryofibrinogenemia) or small- and medium-sized vessel vasculitis (Type II and III cryoglobulinemia) with emphasis on lesion morphology and cutaneous manifestations. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - dermatology.mhmedical.com/content.aspx?aid=1161350253 ER -