TY - CHAP M1 - Book, Section TI - Biology of Nails A1 - Scher, Richard K. A1 - Bonilla, Gisela Torres A1 - DeYampert, Nicole A2 - Kelly, A. Paul A2 - Taylor, Susan C. A2 - Lim, Henry W. A2 - Serrano, Ana Maria Anido Y1 - 2016 N1 - T2 - Taylor and Kelly's Dermatology for Skin of Color, 2e AB - KEY POINTSNail matrix melanocytes in skin of color contain mature melanosomes that produce nail plate pigmentation.Melanonychia in multiple nails reduces but does not eliminate the probability of melanoma.Although melanoma of the nail unit is uncommon in skin of color, acral locations, including nails, occur disproportionately more frequently.Over 90% of melanonychias arise from the distal rather than the proximal nail matrix.Melanomas are more frequent in the great toe and thumb than in other digits.Most melanomas arising from melanonychia striata are in situ melanomas. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/20 UR - dermatology.mhmedical.com/content.aspx?aid=1161544804 ER -