TY - CHAP M1 - Book, Section TI - Squamous Cell Carcinoma A1 - Krishna, Sheila M. A1 - Garrett, Algin B. A2 - Kelly, A. Paul A2 - Taylor, Susan C. A2 - Lim, Henry W. A2 - Serrano, Ana Maria Anido Y1 - 2016 N1 - T2 - Taylor and Kelly's Dermatology for Skin of Color, 2e AB - KEY POINTSPrimary carcinoma of the skin is the most common form of cancer diagnosed in the United States, but the incidence in people with skin of color is reported as rare.Most squamous cell carcinomas (SCCs) in people with skin of color occur in non–sun-exposed areas; however, when SCC does occur in a sun-exposed area, the anatomic distribution is similar to that in Caucasians.SCC that occurs in sun-exposed skin has its origin in loss of the organized control of epidermal keratinocyte differentiation secondary to DNA damage as a direct result of ultraviolet light.The factors that are responsible for developing skin cancers in non–sun-exposed areas are unknown.Areas of chronic inflammation, chronic ulceration, and scarring are predisposed to the development of SCC. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/03 UR - dermatology.mhmedical.com/content.aspx?aid=1161546995 ER -