TY - CHAP M1 - Book, Section TI - The Ichthyoses A1 - Choate, Keith A. A1 - Milstone, Leonard M. A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. Y1 - 2019 N1 - T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCEThe ichthyoses are a heterogeneous group of skin diseases characterized by generalized scaling, and often areas of thickened skin.Most types are inherited, and these usually present at birth or appear in childhood; however, some forms are acquired.Scales may vary in size, color, and body site.The may be accompanied by erythema, abnormalities in adnexal structures, and palmoplantar keratoderma.The may be associated with systemic findings, such as failure to thrive, increased susceptibility to infection, atopic dermatitis, neurosensory deafness, and neurologic and other disease.Histopathology is usually nonspecific with few notable exceptions.Early genetic testing can aid in the diagnosis and anticipation of potential systemic abnormalities. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - dermatology.mhmedical.com/content.aspx?aid=1162814911 ER -