TY - CHAP M1 - Book, Section TI - Skin Diseases of the Feet A1 - Schultz, Brittney A1 - Goldfarb, Noah A2 - Soutor, Carol A2 - Hordinsky, Maria K. Y1 - 2022 N1 - T2 - Clinical Dermatology: Diagnosis and Management of Common Disorders, 2e AB - Acral surfaces, such as the feet, have unique characteristics that make them prone to certain dermatologic conditions. The plantar surface of the foot has the thickest keratin layer, a high concentration of eccrine sweat glands as well as sensory nerves, Pacinian corpuscles and other mechanoreceptors. The combination of abundant keratin and sweat creates an ideal environment for fungal infections. Friction and contact with footwear also make the feet susceptible to contact dermatitis. In addition, the feet are disproportionately affected by vascular disorders, due to their gravity-dependent anatomical location, and by peripheral small fiber sensory neuropathies. Since the feet are a site of frequent injury, vascular disorders and sensory neuropathies predispose this area to recurrent and difficult to manage wounds. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/11/05 UR - dermatology.mhmedical.com/content.aspx?aid=1190940310 ER -