TY - CHAP M1 - Book, Section TI - Diabetes and Other Endocrine Diseases A1 - Schachtel, April A1 - Kalus, Andrea A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. PY - 2019 T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCEThe incidence of diabetes in America is increasing steadily with the epidemic of obesity.Fourteen percent of health care expenditures in America are diabetes related.Metabolic abnormalities in glucose and insulin relate directly to diabetic thick skin, limited joint mobility, eruptive xanthomas, and acanthosis nigricans.Neuropathy, vasculopathy, and immune dysfunction associated with diabetes contribute directly to lower-extremity ulcers and certain cutaneous infections.Diabetes-associated skin conditions without a known pathogenesis include: necrobiosis lipoidica, granuloma annulare, diabetic dermopathy, acquired perforating dermatosis, and bullosis diabeticorum. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - dermatology.mhmedical.com/content.aspx?aid=1161349599 ER -