TY - CHAP M1 - Book, Section TI - Interface Dermatitis A1 - Horn, Thomas D. A1 - Junkins-Hopkins, Jacqueline M. A2 - Barnhill, Raymond L. A2 - Crowson, A. Neil A2 - Magro, Cynthia M. A2 - Piepkorn, Michael W. A2 - Kutzner, Heinz A2 - Desman, Garrett T. PY - 2020 T2 - Barnhill's Dermatopathology, 4e AB - A large group of skin diseases is characterized by histologic changes categorized as interface dermatitis (Fig. 3-1). At a minimum, a variable combination of leukocyte infiltration of the dermis, vacuolar change of the basilar epidermis, accumulation of melanophages in the upper dermis, and necrosis of keratinocytes must be observed. The term “interface dermatitis” is therefore apt because these findings occur at the interface between the epidermis and dermis. This common thread binds otherwise disparate entities together. Other terms applied to this group of disorders include vacuolar dermatitis, vacuolar interface dermatitis, and lichenoid tissue reaction. Before considering specific diseases, a definition and illustration of the common histologic findings are in order. SN - PB - McGraw Hill Education CY - New York, NY Y2 - 2024/04/19 UR - dermatology.mhmedical.com/content.aspx?aid=1178387622 ER -