TY - CHAP M1 - Book, Section TI - Intraepidermal Vesiculopustular Diseases A1 - Magro, Cynthia M. A1 - Crowson, A. Neil A1 - Harrist, Terence J. A2 - Barnhill, Raymond L. A2 - Crowson, A. Neil A2 - Magro, Cynthia M. A2 - Piepkorn, Michael W. A2 - Kutzner, Heinz A2 - Desman, Garrett T. PY - 2020 T2 - Barnhill's Dermatopathology, 4e AB - A wide variety of disorders may produce intraepidermal vesicles and pustules. Distinct diseases may have similar or even identical pathologic features. In addition, the histopathologic findings in each disease evolve over time. Thus the algorithmic approach to diagnosis in this group is, of necessity, complex but facilitates the diagnosis in this group of disorders (Figs. 7-1, 7-2, 7-3, Table 7-1), and especially when correlated to clinical and historical data often proves essential. The algorithm narrows the differential diagnosis to a few entities or a specific diagnosis through evaluation of the blister-cleft separation plane, the principal pathologic process, and if present, the inflammatory cell complement. Immunofluorescent and/or serologic studies are of paramount importance. SN - PB - McGraw Hill Education CY - New York, NY Y2 - 2024/04/20 UR - dermatology.mhmedical.com/content.aspx?aid=1178388888 ER -