TY - CHAP M1 - Book, Section TI - Botulinum Toxin A1 - Baumann, Leslie A1 - Elsaie, Mohamed L. A1 - Grunebaum, Lisa A2 - Baumann, Leslie A2 - Saghari, Sogol A2 - Weisberg, Edmund PY - 2009 T2 - Cosmetic Dermatology: Principles and Practice, 2e AB - Botulinum toxin (BTX), an exotoxin produced by the bacteria Clostridium botulinum, occurs naturally in nature. BTX induces a bilaterally symmetric descending neuroparalytic condition called botulism. The word “botulinum” is derived from the Latin word for sausage, “botulus.” Botulism was so named during the Napoleonic Empire in the early 1800s when it was noted to be triggered by the ingestion of spoiled sausages. Later, German physician Justinus Kerner described food-borne botulism and its clinical symptoms during the period between 1817 and 1822. In 1946, Schantz reported isolating BTX type A in its crystalline form, and nearly a quarter of a century later, Alan Scott became the first to harness the effects of BTX for medicinal use in monkey strabismus.1 SN - PB - The McGraw-Hill Companies, Inc. CY - New York, NY Y2 - 2024/04/18 UR - dermatology.mhmedical.com/content.aspx?aid=1172446995 ER -