TY - CHAP M1 - Book, Section TI - Preservatives A1 - Weisberg, Edmund A1 - Baumann, Leslie A2 - Baumann, Leslie A2 - Saghari, Sogol A2 - Weisberg, Edmund PY - 2009 T2 - Cosmetic Dermatology: Principles and Practice, 2e AB - Preservatives are integral ingredients in various food, pharmaceutical, cosmetic, and skin care formulations. As water is included in the majority of such products, preservatives are added to prevent the growth of microorganisms and the resultant rapid deterioration or decomposition of the product. Indeed, without preservatives, which are biocidal chemicals, these items important to daily life would exhibit little to no shelf life and become quickly invaded and permeated by numerous bacteria, fungi, and molds. As such, preservatives are intended to maintain the integrity of the product and protect the user from infection.1 While antimicrobial preservatives are essential components in the majority of cosmetics and skin care products, these ingredients have been cited frequently as causes of allergic contact dermatitis.1–3 Such occurrences are most often associated with topical application on damaged or broken skin. Of greater concern in recent years has been the reports linking the use of some skin care products with cancer incidence. This chapter will focus on the most frequently used class of preservatives, recent data regarding the estrogenic potential of these compounds, and the controversy regarding possible associations between the chronic use of chemical preservatives that make contact with the skin and cancer. SN - PB - The McGraw-Hill Companies, Inc. CY - New York, NY Y2 - 2024/04/17 UR - dermatology.mhmedical.com/content.aspx?aid=1172448345 ER -