TY - CHAP M1 - Book, Section TI - Genital Cancers A1 - Perez, Mariana E. A1 - Williams, Natalie M. A1 - Cerwinka, Wolfgang H. A1 - Block, Norman L. A1 - Kava, Bruce R. A2 - Nouri, Keyvan PY - 2023 T2 - Skin Cancer: A Comprehensive Guide AB - SUMMARYTumors can arise from any tissue within the penis or the vulva, and benign lesions are likely underreported. Treatment may range from simple observation to radical excision, depending on tumor features and patient symptoms.Likewise, scrotal tumors can arise from either the overlying epidermis or underlying dermal structures, though they are usually rare.Squamous cell carcinoma is the most common malignancy of the penis, vulva, and scrotum. Metastasis occurs primarily to the inguinal lymph nodes, and treatment is determined based on the stage of the disease.Extramammary Paget disease is more common among females and is considered premalignant by many, though lesions often appear benign. Surgery is the standard of treatment, but recurrence is common. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - dermatology.mhmedical.com/content.aspx?aid=1194725912 ER -