TY - CHAP M1 - Book, Section TI - Photodynamic Therapy A1 - Tsoukas, Maria A1 - Puyana, Carolina A2 - Nouri, Keyvan PY - 2023 T2 - Skin Cancer: A Comprehensive Guide AB - SUMMARYPhotodynamic therapy (PDT) consists of interaction between a photosensitizer, light, and oxygen, resulting in the production of reactive oxygen species, which leads to targeted cell death.The two main topical photosensitizer prodrugs approved by the U.S. Food and Drug Administration (FDA) in the United States are 5-aminolevulinic acid (ALA) and its methylated derivative, methyl aminolevulinate (MAL).PDT is a safe and effective treatment methodology that is commonly used for actinic keratosis (AK), actinic cheilitis, and superficial nonmelanoma skin cancers. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - dermatology.mhmedical.com/content.aspx?aid=1194728127 ER -