TY  - CHAP
M1  - Book, Section
TI  - Topical 5-Fluorouracil
A1  - Masciarella, Andrew D.
A1  - Tang, Jennifer C.
A2  - Nouri, Keyvan
PY  - 2023
T2  - Skin Cancer: A Comprehensive Guide
AB  - SUMMARYThe  antimetabolites  of  5-FU  disrupt  cell  functioning  through  inhibiting  nucleotide  creation  and  incorporation  into  DNA  and  RNA.5-FU  is  indicated  for  treating  actinic  keratosis  and  superficial  basal  cell  carcinoma.5-FU  has  been  used  as  off-label  treatment  for  squamous  cell  carcinoma  in  situ,  actinic  chelitis,  keratoacanthomas,  among  others.1%,  2%,  and  5%  preparations  typically  follow  a  once-  or  twice-daily  application,  while  0.5%  cream  follows  a  once-daily  application  for  a  duration  dependent  on  the  indication,  anatomic  location,  and  patient  sensitivity  to  treatment.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - dermatology.mhmedical.com/content.aspx?aid=1194728415
ER  -