TY - CHAP M1 - Book, Section TI - Oily Skin A1 - Baumann, Leslie S. A2 - Baumann, Leslie S. A2 - Rieder, Evan A. A2 - Sun, Mary D. PY - 2022 T2 - Baumann’s Cosmetic Dermatology, 3e AB - SUMMARY POINTSWhat’s Important?Oxidation of squalene in sebum leads to comedones and milia.Oxidized squalene (squalene peroxides) has deleterious effects on skin including aging.The Baumann Skin Type Indicator Questionnaire can accurately predict sebum secretion rates.The average sebum production rate is 1 mg/10 cm2 every 3 hours.What’s New?Oily skin is divided into normal oily skin and very oily skin.Normal oily skin has normal sebum secretion rates.Botulinum toxin Type A reduces sebum production.Various cannabinoids affect sebum production differently.What’s Coming?PPAR and retinoid X receptor agonists and antagonists may be developed topically to control sebum production.The effect of diabetes medications and insulin-like growth factor-1 (IGF-1) on sebum secretion is yet to be established.Autophagy regulates sebum production and is suppressed by testosterone as well as IGF-1 and increased by vitamin D. Development of products that increase autophagy in sebocytes may lead to agents to decrease skin oiliness.More data are needed to compare differences in sebum secretion rates among different ethnicities. SN - PB - McGraw Hill LLC CY - New York, NY Y2 - 2024/04/18 UR - dermatology.mhmedical.com/content.aspx?aid=1197533171 ER -