TY - CHAP M1 - Book, Section TI - Antioxidants A1 - Baumann, Leslie S. A1 - Weisberg, Edmund M. A2 - Baumann, Leslie S. A2 - Rieder, Evan A. A2 - Sun, Mary D. PY - 2022 T2 - Baumann’s Cosmetic Dermatology, 3e AB - SUMMARY POINTSWhat’s Important?Antioxidants protect against the ravages of free radicals by reducing and neutralizing them.Antioxidants may be particularly useful in UVA-induced skin alterations that are believed to be determined, in large part, by oxidative processes.Topical antioxidants are currently marketed for the prevention of aging and UV-mediated skin damage as well as the treatment of wrinkles and erythema due to inflammation, such as that induced by laser resurfacing.The free radical theory of aging explains why antioxidants are thought to prevent wrinkles, but this theory does not justify the use of antioxidants to treat wrinkles that are already present.What’s New?New antioxidants are being introduced into the market frequently.Using combinations of antioxidant types is preferred rather than one antioxidant.Antioxidants should be included in diet, beverages, and supplements in addition to topical skincare products.What’s Coming?New methods are needed to quantify antioxidant strength so that efficacy between types can be compared. Current antioxidant quantitative measurements such as the ORAC value pertain to foods, not topical products.Antioxidants are being evaluated to protect mitochondria and other cellular components. SN - PB - McGraw Hill LLC CY - New York, NY Y2 - 2024/03/29 UR - dermatology.mhmedical.com/content.aspx?aid=1197535942 ER -