TY  - CHAP
M1  - Book, Section
TI  - Slide Preparation and Immunohistochemistry
A1  - Emanuel, Patrick
A1  - Cavanagh, Martin
A2  - Emanuel, Patrick
A2  - Izzard, Mark
PY  - 2023
T2  - Margin Control Surgery of the Skin: Concepts, Histopathology, and Applications
AB  - High-quality  staining  is  central  to  the  successful  interpretation  of  pathology  slides.  In  fact,  it  is  probably  not  advisable  to  consider  doing  margin  control  surgery  (MCS)  without  a  well-equipped  laboratory  and  trusted  staff.  Most  laboratories  use  the  hemotoxylin  and  eosin  (HE)  stain  to  colorize  slides.  This  picks  up  the  various  tissue  and  cellular  components  in  different  ways,  resulting  in  a  highly  reproducible  artifact  allowing  assessment  of  the  cellular  and  tissue  morphology.  Pathologists  use  these  staining  characteristics  to  make  determinations  about  the  features  of  disease  they  see  microscopically.  In  a  sense,  it  is  medicine’s  version  of  physiognomy,  the  study  of  how  someone’s  personality  can  be  determined  just  by  looking  at  their  facial  characteristics.  Though  it  may  seem  superficial  and  far  less  sophisticated  than  an  involved  genetic  analysis,  the  centuries-old  method  of  HE  staining  continues  to  be  the  gold  standard  in  diagnostic  pathology.  
SN  - 
PB  - McGraw Hill
CY  - New York, NY
Y2  - 2024/04/25
UR  - dermatology.mhmedical.com/content.aspx?aid=1199482893
ER  -