RT Book, Section A1 Prose, Neil S. A1 Kristal, Leonard SR Print(0) ID 1133963905 T1 Genodermatoses T2 Weinberg's Color Atlas of Pediatric Dermatology, 5e YR 2017 FD 2017 PB McGraw-Hill Education Medical PP New York, NY SN 9780071792257 LK dermatology.mhmedical.com/content.aspx?aid=1133963905 RD 2024/03/29 AB Figure 14-1Pseudoxanthoma elasticum This is a generalized condition in which elastic fibers are degenerative. Clinical signs of the phenomenon can be recognized in the skin and eyes. In the skin, patches of yellowish discoloration and general laxness or redundancy develop on the neck (“chicken skin”), in the axillae, and in other places, such as the fossae of limbs and the inguinal folds, where considerable movement of skin is normal. In the eye, angioid streaks can be seen. They represent the result of faulty elastic fibers in Bruch membrane and generally precede the cutaneous changes. These eye changes frequently result in the loss of central vision and sometimes result in almost complete blindness. Peripheral vision is maintained.Graphic Jump LocationView Full Size||Download Slide (.ppt)