RT Book, Section
A1 Stingl, Georg
A1 Brüggen, Marie-Charlotte
A2 Kang, Sewon
A2 Amagai, Masayuki
A2 Bruckner, Anna L.
A2 Enk, Alexander H.
A2 Margolis, David J.
A2 McMichael, Amy J.
A2 Orringer, Jeffrey S.
SR Print(0)
ID 1161321000
T1 The Immunological Structure of the Skin
T2 Fitzpatrick's Dermatology, 9e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071837798
LK dermatology.mhmedical.com/content.aspx?aid=1161321000
RD 2024/04/18
AB At-A-GlanceSkin  is  a  “Grenzorgan”  equipped  with  the  capacity  to  mount  and  execute  immune  responses.The  cutaneous  immune  system  disposes  of  an  innate  and  adaptive  arm  to  exert  these  functions.Molecular  constituents  of  the  cutaneous  immune  system  include  pattern  recognition  receptors  and  effector  molecules.Tissue  homeostasis  requires  the  prevention  of  exaggerated  responses  to  innocuous  substances  and  the  occurrence  of  host-defense  reactions  at  a  subclinical  level,  ie,  in  the  absence  of  inflammation.Under  pathological  conditions,  danger  signals  or  other  disease-eliciting/-promoting  factors  in  the  skin  elicit  a  coordinated  (host  defense)  reaction  of  its  cellular  and  molecular  elements.