RT Book, Section
A1 Perng, Powell
A1 Sander, Inbal
A2 Kang, Sewon
A2 Amagai, Masayuki
A2 Bruckner, Anna L.
A2 Enk, Alexander H.
A2 Margolis, David J.
A2 McMichael, Amy J.
A2 Orringer, Jeffrey S.
SR Print(0)
ID 1161325686
T1 Fox-Fordyce Disease
T2 Fitzpatrick's Dermatology, 9e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071837798
LK dermatology.mhmedical.com/content.aspx?aid=1161325686
RD 2024/04/24
AB AT-A-GLANCEA  rare,  itchy,  chronic  papular  eruption  localized  to  apocrine  gland–bearing  areas  of  the  body  with  unclear  etiology.Females  are  disproportionately  affected  compared  to  males  (9:1),  with  age  of  onset  most  commonly  between  13-35  years  of  age.Hyperkeratotic  plugging  of  the  follicular  infundibulum  at  the  apocrine  gland  duct  insertion  site  is  thought  to  be  the  primary  pathophysiologic  event,  leading  to  duct  dilation,  rupture,  inflammation,  and  pruritus.No  definitive  cure;  oral  antihistamines  and  topical  clindamycin  may  help  alleviate  symptoms  and  induce  remission.