RT Book, Section A1 Kurtzman, Drew A1 Vleugels, Ruth Ann A2 Kang, Sewon A2 Amagai, Masayuki A2 Bruckner, Anna L. A2 Enk, Alexander H. A2 Margolis, David J. A2 McMichael, Amy J. A2 Orringer, Jeffrey S. SR Print(0) ID 1161350381 T1 Raynaud Phenomenon T2 Fitzpatrick's Dermatology, 9e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071837798 LK dermatology.mhmedical.com/content.aspx?aid=1161350381 RD 2024/04/24 AB AT-A-GLANCERaynaud phenomenon is a vascular disorder characterized by recurrent episodic attacks of digital ischemia provoked by exposure to cold or emotional stress.Affects up to 10% of the population, 4:1 female-to-male ratio.Classified as primary (idiopathic) and secondary (underlying disease or cause present) forms; severity ranges from mild/benign to severe with loss of tissue and risk of amputation.Connective tissue diseases, particularly systemic sclerosis, are among the most common underlying causes of secondary Raynaud phenomenon.Behavioral modification, pharmacologic therapies, and surgical interventions are effective at reducing the frequency and severity of attacks.