RT Book, Section A1 Tharp, Michael D. A2 Kang, Sewon A2 Amagai, Masayuki A2 Bruckner, Anna L. A2 Enk, Alexander H. A2 Margolis, David J. A2 McMichael, Amy J. A2 Orringer, Jeffrey S. SR Print(0) ID 1161343969 T1 Antihistamines T2 Fitzpatrick's Dermatology, 9e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071837798 LK dermatology.mhmedical.com/content.aspx?aid=1161343969 RD 2024/04/19 AB AT-A-GLANCEH1 antihistamines are first-line therapy for chronic idiopathic and physical urticarials.H1 agents may be useful in treating conditions with histamine-associated pruritus.Limited evidence supports the use of H1 in the treatment of atopic dermatitis.Certain special patient populations, including children, the elderly, and patients with renal or hepatic impairment, may require dosage adjustments when using antihistamines.H2 antihistamines may be a useful adjunct to H1 antihistamine therapy in refractory cases of chronic idiopathic urticaria/angioedema.