RT Book, Section
A1 Onyekonwu, Chinwe Laura
A1 Ozoh, Gladys Angela
A1 Ojinmah, Uche Rowland
A2 Kelly, A. Paul
A2 Taylor, Susan C.
A2 Lim, Henry W.
A2 Serrano, Ana Maria Anido
SR Print(0)
ID 1161548564
T1 Onchocerciasis
T2 Taylor and Kelly's Dermatology for Skin of Color, 2e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071805520
LK dermatology.mhmedical.com/content.aspx?aid=1161548564
RD 2024/04/24
AB KEY  POINTSOnchocerciasis  is  a  chronic,  disabling  vector-borne  disease  caused  by  infestation  with  the  filarial  nematode  worm  Onchocerca  volvulus  that  not  only  leads  to  physical  and  psychosocial  sequelae,  but  also  causes  profound  socioeconomic  problems.An  estimated  37  million  people  are  afflicted,  especially  in  sub-Saharan  Africa,  with  Nigeria  accounting  for  about  one-third  of  the  world’s  cases.Clinical  presentation  reflects  variations  in  a  host’s  immune  response  to  the  parasite.The  classic  lesion  is  the  onchocercoma,  a  firm,  painless  nodule  that  occurs  in  the  subcutaneous  tissue.Most  of  the  burden  of  the  skin  disease  occurs  as  a  result  of  severe,  intolerable  pruritus.Mass  treatment  with  ivermectin  in  affected  communities  has  been  highly  successful  in  reducing  the  disease  burden.There  remains  a  need  for  sustainability  of  control  measures  to  maintain  the  gains  in  management  of  the  disease.