RT Book, Section
A1 Anhalt, Grant J.
A1 Mimouni, Daniel
A2 Kang, Sewon
A2 Amagai, Masayuki
A2 Bruckner, Anna L.
A2 Enk, Alexander H.
A2 Margolis, David J.
A2 McMichael, Amy J.
A2 Orringer, Jeffrey S.
SR Print(0)
ID 1162815761
T1 Paraneoplastic Pemphigus
T2 Fitzpatrick's Dermatology, 9e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071837798
LK dermatology.mhmedical.com/content.aspx?aid=1162815761
RD 2024/04/18
AB AT-A-GLANCERare  complication  of  malignancy,  most  commonly  non-Hodgkin  lymphoma,  chronic  lymphocytic  leukemia,  or  Castleman  disease.Painful,  erosive  stomatitis  and  polymorphous  cutaneous  lesions  that  may  be  blistering  and  erosive  (resembling  erythema  multiforme),  morbilliform,  or  lichenoid.Serum  autoantibodies  directed  against  plakin  proteins  that  are  detected  by  indirect  immunofluorescence  against  rodent  bladder  epithelium.High  mortality  rate,  with  death  from  sepsis,  complications  of  treatment,  or  bronchiolitis  obliterans.No  consistently  effective  therapy,  but  some  success  with  the  combined  use  of  rituximab,  systemic  corticosteroids,  and  other  immunosuppressive  agents.