RT Book, Section A1 Francès, Camille A2 Kang, Sewon A2 Amagai, Masayuki A2 Bruckner, Anna L. A2 Enk, Alexander H. A2 Margolis, David J. A2 McMichael, Amy J. A2 Orringer, Jeffrey S. SR Print(0) ID 1162817500 T1 Relapsing Polychondritis T2 Fitzpatrick's Dermatology, 9e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071837798 LK dermatology.mhmedical.com/content.aspx?aid=1162817500 RD 2024/03/28 AB AT-A-GLANCERelapsing polychondritis is a rare multisystem autoimmune disease.Different factors are implicated in the pathogenesis, including a genetic susceptibility, immunization against cartilaginous structures, and modification of cytokine and chemokine signatures.More than 30% of patients have an associated disease, mainly of autoimmune or hematologic origin.Recurrent episodes of chondritis lead to progressive destruction of cartilaginous structures.Other proteoglycan-rich structures, such as eyes, blood vessels, or inner ear, are also affected.Dermatologic manifestations occur frequently, especially in association with myelodysplasia. They are nonspecific and resemble those observed in Behçet disease and inflammatory bowel diseases.